



Designs for Health Liposomal B Supreme is a liquid B-complex supplement that utilizes liposomal technology, a delivery method intended to enhance nutrient absorption. Unlike traditional capsules or tablets, this formula is designed to be held in the mouth before swallowing, allowing for better uptake through the mucous membranes.
This product contains all eight essential B vitamins, as well as Betaine to support methylation and Milk Thistle to promote bile flow. However, while it includes bioactive forms of some vitamins, others are not in their most effective forms. Additionally, the formula contains preservatives and additives, which may be a drawback for those seeking a cleaner supplement.
Liposomal B Supreme provides a full spectrum of B vitamins, including methylcobalamin (B12) and riboflavin-5-phosphate (B2), which are considered highly bioavailable. The inclusion of Betaine (trimethylglycine) is a notable benefit, as it aids in methylation, a process critical for neurotransmitter function and cardiovascular health. The liposomal delivery method is another key advantage, as it enhances absorption compared to standard oral supplements.
However, there are some shortcomings. The product uses calcium folinate instead of Quatrefolic®, a more stable, bioavailable folate form that is more suitable for people with MTHFR mutations. Furthermore, Liposomal B Supreme provides its B6 in the form of pyridoxine HCl rather than the superior P5P (pyridoxal-5-phosphate). Additionally, there is no Choline, which works synergistically with B vitamins to support DNA health. While the formula is effective for many, these factors make it slightly less optimal compared to other premium B-complex supplements.
This product is third-party tested and manufactured under Good Manufacturing Practices (GMP), ensuring quality and purity. It is free from common allergens and contains no artificial colors or flavors. However, it does include preservatives such as EDTA, which may not be ideal for those avoiding additives. Additionally, the label includes a warning for pregnant and breastfeeding women to consult a healthcare provider before use, which is good advice even if you’re not pregnant or nursing. You should consult with a doctor before starting any supplements. While the doses of most B vitamins are within safe limits, the high concentration of certain nutrients may not be necessary for everyone and could lead to excessive intake over time.
Designs for Health Liposomal B Supreme offers a unique liquid delivery system that may enhance absorption compared to standard capsules. It includes all essential B vitamins along with Betaine and Milk Thistle for additional health benefits. However, the formula has some drawbacks, including the use of less bioavailable B6 and folate forms, the absence of Choline, and the inclusion of preservatives. Additionally, there is no mention of a satisfaction guarantee or return policy, which could be a concern for customers who prefer a risk-free purchase. Overall, while this is a decent B-complex option, those looking for the most complete and effective formula may want to consider other alternatives.